Wednesday, March 11, 2009

Pregabalin


Pregabalin (INN) (pronounced /prɨˈgæbəlɨn/) is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults.[1] It has also been found effective for generalized anxiety disorder and is (as of 2007) approved for this use in Europe.[1] It was designed as a more potent successor to gabapentin. Pregabalin is marketed by Pfizer under the trade name Lyrica.
Recent studies have shown that pregabalin is effective at treating chronic pain in disorders such as fibromyalgia[2] and spinal cord injury.[3] In June 2007, pregabalin became the first medication approved by the U.S. Food and Drug Administration specifically for the treatment of fibromyalgia.[4]
It is considered to have a low potential for abuse, and a limited dependence liability if misused, and is thus classified as a Schedule V drug in the U.S.[5]

Nerve Pain after Herpes, Diabetic Complication causing Injury to some Body Nerves, Additional Medication to Treat Partial Seizures, Disorder characterized by Stiff, Tender & Painful Muscles. Lyrica Oral may also be used to treat Neuropathic Pain. This medication is used to treat pain caused by nerve damage due to diabetes and shingles (herpes zoster) infection. It is also used to treat pain in people with fibromyalgia. It is also used with other medications to treat certain types of seizures (partial onset seizures).
Pregabalin is indicated for:
Treatment of neuropathic pain from diabetic neuropathy or post herpetic neuralgia. There is not enough data to state that it should be used in all neuropathic pain.
Adjunctive therapy in adults with partial seizures with or without secondary generalization
Fibromyalgia pain
Generalized anxiety disorder (approved in the European Union).[8]

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